Who Controls Me?

Genesis 48

But Israel reached out his right hand and put it on Ephraim's head though he was the younger, and crossing his arms, he put his left hand on Manasseh's head; even though Manasseh was the firstborn.
Genesis 48:14

How did Jacob know to do this? Was he only showing preference for the younger one because he was a younger brother? I think God gave him a special anointing of the Holy Spirit at that time. If this had just been his personal preference, then it wouldn't have come true.

Lord, I want to be so in tune with you and your Holy Spirit that I always speak your words instead of my own and always react and do what you would instead of the way my flesh would choose to.

Those who are dominated by the sinful nature think about sinful things, but those who are controlled by the Holy Spirit think about things that please the Spirit. If your sinful nature controls your mind, there is death. But if the Holy Spirit controls your mind, there is life and peace.
Romans 8:5-6 NLT

So, dear brothers and sisters, you have no obligation whatsoever to do what your sinful nature urges you to do. For if you keep on following it, you will perish. But if through the power of the Holy Spirit you turn from it and its evil deeds, you will live. For all who are led by the Spirit of God are children of God.
Romans 8:12-14 NLT